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5-HT Receptor


5-HT receptors (5-hydroxytryptamine receptors,The serotonin receptors) are a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs) found in the central and peripheral nervous systems. They mediate both excitatory and inhibitory neurotransmission. The serotonin receptors are activated by the neurotransmitter serotonin, which acts as their natural ligand.

  • Granisetron HCl EY1310

    Granisetron Hydrochloride是5-HT3受体拮抗剂，可作为化疗后止吐剂。

    More

  • Amfebutamone HCl EY1308

    Amfebutamone HCl是一种选择性去甲肾上腺素-多巴胺再摄取的抑制剂，IC50分别为6.5和3.4μM。

    More

  • Zolmitriptan EY1302

    Zolmitriptan (佐米曲普坦) 是五羟色胺受体1B和1D亚型激动剂。

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  • SB742457 EY1131

    SB742457是5-HT6受体拮抗剂，pKi为9.63，比对其它受体的抑制性高100倍以上。

    More

  • SB269970 HCl EY0909

    SB269970盐酸盐是5-HT7受体拮抗剂，pKi为8.3，比对其它受体的抑制性高50倍以上。

    More

  • Granisetron HCl EY1310

    Granisetron Hydrochloride是5-HT3受体拮抗剂，可作为化疗后止吐剂。

    More

  • Amfebutamone HCl EY1308

    Amfebutamone HCl是一种选择性去甲肾上腺素-多巴胺再摄取的抑制剂，IC50分别为6.5和3.4μM。

    More

  • Zolmitriptan EY1302

    Zolmitriptan (佐米曲普坦) 是五羟色胺受体1B和1D亚型激动剂。

    More

  • SB742457 EY1131

    SB742457是5-HT6受体拮抗剂，pKi为9.63，比对其它受体的抑制性高100倍以上。

    More

  • SB269970 HCl EY0909

    SB269970盐酸盐是5-HT7受体拮抗剂，pKi为8.3，比对其它受体的抑制性高50倍以上。

    More
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